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1 associated gene
No signs/symptoms info
COMMON GENES: 1
1 OMIM reference -
5 associated genes
13 signs/symptoms
Zollinger-Ellison syndrome
Multiple endocrine neoplasia type 1

MEN1 CDKN1A
CDKN1B
CDKN2B
CDKN2C
MEN1


COMMON
GENES
MEN1



Citations in the biomedical literature:


Zollinger-Ellison syndrome
MEN1
Multiple endocrine neoplasia type 1
CDKN1A CDKN1B CDKN2B CDKN2C



Zollinger-Ellison syndrome
Multiple endocrine neoplasia type 1

Synonym(s):
- Gastrinoma

Synonym(s):
- MEN 1
- Wermer syndrome

Classification (Orphanet):
- Rare endocrine disease
- Rare gastroenterologic disease
- Rare oncologic disease
Classification (Orphanet):
- Rare endocrine disease
- Rare gastroenterologic disease
- Rare genetic disease
- Rare oncologic disease

Classification (ICD10):
- Endocrine, nutritional and metabolic diseases -
Classification (ICD10):
- Neoplasms -

Epidemiological data:
Class of prevalence: 1-9 / 100 000
Average age onset: adulthood
Average age of death: normal
Type of inheritance: sporadic
Epidemiological data:
Class of prevalence: 1-9 / 100 000
Average age onset: variable
Average age of death: adult
Type of inheritance: autosomal dominant

External references:
No OMIM references
2 MeSH references: D015043 / D015408
External references:
1 OMIM reference -
1 MeSH reference: D018761

Multiple endocrine neoplasia type 1

Very frequent
- Anomalies of the endocrine glands
- Anomaly of pancreatic hormones
- Autosomal dominant inheritance
- Hypercalcemia
- Hyperparathyroidy
- Hypothalamic-hypophyseal axis anomalies / hypothalamus / pituitary anomalies
- Neoplasms / tumors
- Parathyroids anomalies
- Structural anomalies of the pancreas

Frequent
- Cortico-adrenal hyperplasia / hypersecretion
- Epigastralgia / heartburn / gastric / duodenal ulcer / gastritis
- Thyroid anomalies
- Xanthomas / lipomas



Zollinger-Ellison syndrome

(no data available)